Find out if you or your partner are carriers of a hereditary disease before starting your assisted reproduction treatment.
Approximately 1% of children are born with genetically based diseases. They can be inherited or occur “novo”, most of them being the latter.
Almost everyone is a healthy carrier of a recessive hereditary disease of which they are often unaware. If your partner is also a carrier of the same alteration in your genes, the risk that your child will have the disease is 25%.
The “Genetic Compatibility Test” is a blood test that detects these genetic mutations (currently the 420 genes that cause the most frequent diseases). It analyses, through massive sequencing and other techniques, 420 genes related to recessive or X-linked pathologies, in order to assess reproductive risk. By comparing the results of both members of a couple, we will know if they are both carriers of the same alteration.
If there is genetic incompatibility with respect to a serious disease, in an In Vitro Fertilisation treatment, the embryos can be genetically analysed and the affected embryos can be avoided to be transferred. This study can also be carried out later, during pregnancy, on the foetus.
Genetic screening does not “ensure” the birth of healthy children; it is impossible to avoid all the risks in the offspring. At Institut Marquès we believe that the best thing to do is to inform all patients about the general genetic risk and yours in particular, and we offer to carry out this analysis in our own centre.